Much of the new expansion revolves around traveling at sea, specifically to unique uncharted islands not yet found on the game's world map. These procedurally-generated islands are ripe with loot to plunder, should you meet their unique challenges. Blizzard has developed advanced A.I. that more closely resembles unpredictable player behavior, so you'd better bring your A-game if you want to defeat those who are also seeking the island's treasures.
Chilled to the Bone, Dampened Magic, Kleptomania, Netherwind Armor, Prismatic Cloak, and Temporal Shield have limited use in PvE content in terms of increasing your damage in the open world, but they can be situationally useful. Notably Temporal Shield can be utilized for, functionally, an extra 6 seconds of combat time against large elite mobs.